Primary prevention of natural rubber latex allergy in the German health care system through education and intervention. Natural rubber latex allergy: spectrum, diagnostic approach, and therapy. Woods JA, Lambert S, Platts-Mills TA, Drake DB, Edlich RF. Latex sensitization in dental students using powder-free gloves low in latex protein: a cross-sectional study. Schmid K, Christoph Broding H, Niklas D, Drexler H. Natural rubber latex allergy among health care workers: a systematic review of the evidence. Latex symptoms and sensitisation in health care workers. Larese Filon F, Bosco A, Fiorito A, Negro C, Barbina P. Latex provocation tests in patients with spina bifida: who is at risk of becoming symptomatic?. Prevalence of and risk factors for latex sensitization in patients with spina bifida. Allergic contact dermatitis from natural rubber latex without immediate hypersensitivity. Widespread adoption of nonlatex or low-latex gloves has decreased the incidence of latex sensitization in health care workers. The use of nonlatex products from birth may prevent potentially serious allergic reactions. The main goals of latex allergy management are avoidance of exposure to latex allergens and appropriate treatment of allergic reactions. Latex allergy can be diagnosed with clinical history, skin prick testing, latex-specific serum immunoglobulin E testing, and glove provocation testing. Reactions to latex allergy can range from type IV delayed hypersensitivity (e.g., contact dermatitis) to type I immediate hypersensitivity (e.g., urticaria, bronchospasm, anaphylaxis). Children with spina bifida and others who undergo multiple surgeries or procedures, particularly within the first year of life, are also at greater risk of latex allergy. The prevalence of latex allergy in the general population is low however, the risk of developing latex allergy is higher in persons with increased latex exposure, such as health care workers or persons who work in the rubber industry.
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